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Propranolol plasma clearance was also reduced in the patients with chronic renal failure.

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it may be advisable to withdraw the drug gradually over a period of several weeks depending on the patient s age, comorbidity, and dose of propranolol hydrochloride extended-release capsules, usp.

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in summary, no significant differences were found between propranolol and usual care in terms of mortality and sepsis occurrence.


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