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Midostaurin is a cyp3a4 substrate; indinavir is a strong cyp3a4 inhibitor.

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it is likely that ketoconazole, indinavir, and other cyp3a4 inhibitors such as itraconazole may lead to substantial increases in trazodone plasma concentrations with the potential for adverse effects.

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protease inhibitors, such as atazanavir darunavir fosamprenavir indinavir nelfinavir ritonavir saquinavir simeprevir tipranavir non-nucleoside reverse transcriptase inhibitors, such as etravirine entry inhibitors, such as maraviroc integrase inhibitors, such as elvitegravir.

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medicines called nitrates medicines called guanylate cyclase stimulators such as riociguat adempas medicines called hiv protease inhibitors such as ritonavir norvir , indinavir crixivan , saquinavir fortavase or invirase or atazanavir reyataz some types of oral antifungal medicines, such as ketoconazole nizoral and itraconazole sporanox some types of antibiotics, such as clarithromycin biaxin , telithromycin ketek , or erythromycin medicines called alpha-blockers.

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