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Dose-response study in a double-blind, placebo-controlled dose-response study in patients with baseline tg levels from 273 to 817 mg dl, rosuvastatin given as a single daily dose 5 to 40 mg over 6 weeks significantly reduced serum tg levels table 9 .

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rosuvastatin increases the number of hepatic ldl receptors on the cell-surface, enhancing uptake and catabolism of ldl and it inhibits the hepatic synthesis of vldl, thereby reducing the total number of vldl and ldl particles.

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some of the more common side effects associated with rosuvastatin are nausea, stomach pain, constipation, headache, and weakness.


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