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It should be noted that because citalopram is metabolized by multiple enzyme systems, inhibition of one pathway may not appreciably decrease citalopram clearance.

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in conclusion, in contrast to citalopram, mirtazapine reinforces frontocortical dopaminergic and corticolimbic adrenergic, but not serotonergic, transmission.

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some studies also showed no difference in the intellectual development of babies whose mothers took citalopram or escitalopram while breastfeeding.

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